Heldt lab

Welcome to the Heldt Bioseparations Laboratory at Michigan Tech!

The Heldt Bioseparations Lab at Michigan Tech is interested in exploiting surface chemistry to (i) remove and/or purify pathogens and toxins from water and food, (ii) detect pathogens and toxins quickly and easily with point-of-care devices, and (iii) discovering natural antiviral compounds while (iv) educating students in chemical and biological engineering.  We currently work with several viruses to give us a range of sizes, chemical stabilities, and membrane properties that allow us to determine techniques that produce the desired effect in virus removal, purification, and detection systems. 

As recently stated in PNAS (Rappuoli et al. 2014):
"Vaccination is the most effective medical intervention ever introduced and, together with clean water and sanitation, it has eliminated a large part of the infectious diseases that once killed millions of people."

Major Awards
General Research Areas                        
  • Biophysics
  • Molecular recognition
  • Virus structure
  • Antiviral compounds
  • Virus removal and purification                           

Recent Lab News

  • See more of our activities on Twitter
  • Congratulations to Ashish, Pratik and Majid for publishing a paper on mannitol flocculation of virus from our group in Biotechnology Progress (May 2018)
  • Good luck to Seth and Dylan and the rest of the IRES group in Singapore (May 2018)
  • Dr. Heldt received 2nd place in the Best Paper Competition at the ASEE North Central Regional Conference for her work with Wayne County Community College (Mar 2018)
  • Congratulations to Hannah Cunningham for receiving an Honorable Mention in the undergrad poster session at Michigan Tech for her IRES research (Mar 2018)
  • Trying out Nanopartz for gold nanoparticle-antibody conjugates (Jan 2018)
  • Welcome Hassan to the lab (Jan 2018)
  • Congratulations to Pratik for being awarded Best Paper for his session (Oct 2017)
  • Congratulations to Cam and Pratik for each placing 1st in the poster session for the External Advisory Board (Sept 2017)
  • Great video on our NSF IRES Denmark research! (Sept 2017)
  • A nice piece on our trip to Denmark (Jun 2017)
  • Dr. Heldt was recently added to the Editorial Board of Biotechnology Progress (April 2017)
  • Congratulations to Amna, Saagar and Xue for publishing a paper on virus hydrophobicity (April 2017). The paper was highlighted in Science Daily, Science News and was the top story at NSF's Science 360.

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